STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHS1Pleckstrin homology domain containing S1. (469 aa)    
Predicted Functional Partners:
BRAP
BRCA1 associated protein.
      
 0.692
CHCHD5
Coiled-coil-helix-coiled-coil-helix domain containing 5.
      
 0.687
CCDC107
Coiled-coil domain containing 107.
      
 0.636
ZNF395
Zinc finger protein 395.
      
 0.630
ZPLD1
Zona pellucida like domain containing 1.
      
 0.628
TRMT2A
tRNA methyltransferase 2 homolog A; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
      
 0.627
DTWD1
DTW domain containing 1.
      
 0.627
ZGRF1
Zinc finger GRF-type containing 1.
      
 0.624
POU6F2
POU domain protein.
      
 0.597
ING1
Inhibitor of growth protein.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.