STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM7SF3Transmembrane 7 superfamily member 3. (568 aa)    
Predicted Functional Partners:
MRPS35
Mitochondrial ribosomal protein S35.
      
 0.888
INTS13
Integrator complex subunit 13.
      
 0.863
MED21
Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.829
PPFIBP1
PPFIA binding protein 1.
   
  
 0.816
FGFR1OP2
FGFR1 oncogene partner 2.
      
 0.812
LXN
Latexin.
      
 0.718
TMEM63B
Transmembrane protein 63B.
      
 0.635
STK38L
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
      
 0.630
LRMP
Uncharacterized protein.
      
 0.607
DACH1
Dachshund family transcription factor 1.
      
 0.604
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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