STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCLRE1ADNA cross-link repair 1A. (1049 aa)    
Predicted Functional Partners:
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit.
   
 0.816
MCM8
Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family.
   
  
 0.747
FANCM
FA complementation group M.
   
 0.727
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.725
FANCD2
FA complementation group D2.
   
 0.719
XRCC5
X-ray repair cross complementing 5.
   
 
 0.718
FAN1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.700
FANCI
FA complementation group I.
   
 
 0.689
SLX4
SLX4 structure-specific endonuclease subunit.
   
 0.688
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 
 0.688
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.