STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIAESialic acid acetylesterase. (619 aa)    
Predicted Functional Partners:
CD22
CD22 molecule.
      
 0.810
CASD1
CAS1 domain containing 1.
      
 0.803
PLBD2
Phospholipase B-like; Putative phospholipase.
      
 0.746
PRDX6
Peroxiredoxin 6.
      
 0.740
ACTR5
Actin related protein 5; Belongs to the actin family.
      
 0.690
TMEM242
Transmembrane protein 242.
      
 0.663
MUCSM_CANLF
Submaxillary mucin.
    
 
 0.598
AMBP
Alpha-1-microglobulin/bikunin precursor.
      
 0.595
TM6SF1
Transmembrane 6 superfamily member 1.
      
 0.594
PPT1
Palmitoyl-protein thioesterase 1.
      
 0.591
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.