STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGMS2Sphingomyelin synthase 2. (365 aa)    
Predicted Functional Partners:
SMPD1
Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide.
   
 
 0.973
SMPD4
Sphingomyelin phosphodiesterase 4.
   
 
 0.971
UGCG
UDP-glucose ceramide glucosyltransferase.
   
 
 0.970
SMPD2
Sphingomyelin phosphodiesterase 2.
   
 
 0.961
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.957
SMPD3
Sphingomyelin phosphodiesterase 3.
   
 
 0.957
ACER2
Alkaline ceramidase 2.
   
 
 0.946
CERS6
Ceramide synthase 6.
     
 0.945
CERS2
Ceramide synthase 2.
     
 0.944
GBA2
Glucosylceramidase beta 2.
   
 
 0.944
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.