STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)    
Predicted Functional Partners:
ARFGEF1
ADP ribosylation factor guanine nucleotide exchange factor 1.
   
   0.993
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
   
 
 0.834
AKAP10
A-kinase anchoring protein 10.
    
 
 0.774
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.715
DCAF5
DDB1 and CUL4 associated factor 5.
   
  
 0.707
FLNA
Filamin A.
   
 
 0.703
LDLRAD1
Low density lipoprotein receptor class A domain containing 1.
    
 
 0.698
LOC100685875
Small integral membrane protein 15.
      
 0.691
SMIM15
Small integral membrane protein 15.
      
 0.691
LRRC42
Leucine rich repeat containing 42.
      
 0.690
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.