cOR8C5 protein (Canis lupus familiaris) - STRING interaction network

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Score

cOR8C5

G_PROTEIN_RECEP_F1_2 domain-containing protein. (315 aa)

Predicted Functional Partners:

GNAL

0.441

GRK3

0.439

GNG13

0.432

GRK2

0.417

PRKACB

0.412

PRKACA

0.406

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAL	GNG13	ENSCAFP00000053739	ENSCAFP00000029000	G protein subunit alpha L.	G protein subunit gamma 13.	0.960
GNAL	cOR8C5	ENSCAFP00000053739	ENSCAFP00000016546	G protein subunit alpha L.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.441
GNG13	GNAL	ENSCAFP00000029000	ENSCAFP00000053739	G protein subunit gamma 13.	G protein subunit alpha L.	0.960
GNG13	GRK2	ENSCAFP00000029000	ENSCAFP00000017324	G protein subunit gamma 13.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.573
GNG13	PRKACA	ENSCAFP00000029000	ENSCAFP00000053880	G protein subunit gamma 13.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.890
GNG13	PRKACB	ENSCAFP00000029000	ENSCAFP00000030135	G protein subunit gamma 13.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.890
GNG13	cOR8C5	ENSCAFP00000029000	ENSCAFP00000016546	G protein subunit gamma 13.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.432
GRK2	GNG13	ENSCAFP00000017324	ENSCAFP00000029000	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein subunit gamma 13.	0.573
GRK2	GRK3	ENSCAFP00000017324	ENSCAFP00000059736	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.937
GRK2	cOR8C5	ENSCAFP00000017324	ENSCAFP00000016546	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.417
GRK3	GRK2	ENSCAFP00000059736	ENSCAFP00000017324	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.937
GRK3	cOR8C5	ENSCAFP00000059736	ENSCAFP00000016546	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.439
PRKACA	GNG13	ENSCAFP00000053880	ENSCAFP00000029000	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	G protein subunit gamma 13.	0.890
PRKACA	PRKACB	ENSCAFP00000053880	ENSCAFP00000030135	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.987
PRKACA	cOR8C5	ENSCAFP00000053880	ENSCAFP00000016546	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.406
PRKACB	GNG13	ENSCAFP00000030135	ENSCAFP00000029000	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	G protein subunit gamma 13.	0.890
PRKACB	PRKACA	ENSCAFP00000030135	ENSCAFP00000053880	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.987
PRKACB	cOR8C5	ENSCAFP00000030135	ENSCAFP00000016546	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.412
cOR8C5	GNAL	ENSCAFP00000016546	ENSCAFP00000053739	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein subunit alpha L.	0.441
cOR8C5	GNG13	ENSCAFP00000016546	ENSCAFP00000029000	G_PROTEIN_RECEP_F1_2 domain-containing protein.	G protein subunit gamma 13.	0.432