STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAPTM5Lysosomal protein transmembrane 5. (319 aa)    
Predicted Functional Partners:
C1QC
Complement C1q C chain.
   
  
 0.995
C1QA
Complement C1q A chain.
   
  
 0.995
CD53
Tetraspanin.
   
  
 0.929
LAPTM4B
Lysosomal protein transmembrane 4 beta.
     
 0.901
LAPTM4A
Lysosomal protein transmembrane 4 alpha.
     
 0.891
LY86
Lymphocyte antigen 86.
   
  
 0.842
ITGB2
Integrin beta.
   
 
 0.837
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
    0.832
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.816
NCKAP1L
NCK associated protein 1 like.
   
  
 0.773
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.