STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)    
Predicted Functional Partners:
LYNX1
UPAR/Ly6 domain-containing protein.
     
 0.901
RAPSN
Receptor associated protein of the synapse.
   
 
 0.830
ECEL1
Endothelin converting enzyme like 1.
      
 0.730
MUSK
Muscle associated receptor tyrosine kinase.
   
 
 0.714
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
  
 
0.701
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
   
 
 0.692
DOK7
Docking protein 7.
   
  
 0.686
TMTC1
Transmembrane O-mannosyltransferase targeting cadherins 1.
    
 
 0.684
AGRN
Agrin.
   
  
 0.664
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
   
  
 0.646
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.