STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF123Ring finger protein 123. (1314 aa)    
Predicted Functional Partners:
USP19
Ubiquitin specific peptidase 19.
   
 0.952
UBAC1
UBA domain containing 1.
   
 
 0.839
SPATA9
Spermatogenesis associated 9.
      
 0.788
RNF111
Ring finger protein 111.
      
 0.784
CCDC66
Coiled-coil domain-containing protein 66; Microtubule-binding protein required for ciliogenesis. May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites (By similarity). Plays a role in retina morphogenesis and/or homeostasis.
   
  
 0.746
MON1A
MON1 homolog A, secretory trafficking associated.
   
  
 0.720
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
   
  
 0.701
CDHR4
Cadherin related family member 4.
    
 
 0.698
PRCD
Photoreceptor disk component PRCD; Involved in vision.
      
 0.693
ASB6
Ankyrin repeat and SOCS box containing 6.
    
 
 0.692
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.