STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)    
Predicted Functional Partners:
CORO6
Coronin; Belongs to the WD repeat coronin family.
   
   0.931
CORO1B
Coronin; Belongs to the WD repeat coronin family.
   
   0.930
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 
 0.837
SCIN
Scinderin.
   
 
 0.720
ANLN
Anillin actin binding protein.
    
 
 0.688
CORO1A
Coronin; Belongs to the WD repeat coronin family.
    
   0.676
ELANE
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.603
TMOD2
Tropomodulin 2.
   
 
 0.589
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit.
      
 0.529
CNPY2
Saposin B-type domain-containing protein.
      
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.