STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (337 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.977
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.967
MICU2
Mitochondrial calcium uptake 2.
    
 0.949
MCU
Mitochondrial calcium uniporter.
  
 
0.857
MICU3
Mitochondrial calcium uptake family member 3.
     
 0.836
PHB2
Prohibitin.
     
 0.586
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
     
 0.583
PHB
Prohibitin.
     
 0.540
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.540
TXNDC15
Thioredoxin domain containing 15.
    
 
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.