STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISG20Interferon stimulated exonuclease gene 20. (171 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 
 0.810
MX1
Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).
   
  
 0.726
OASL
2'-5' oligoadenylate synthetase-like 1.
   
 
 0.723
IFI35
Interferon induced protein 35.
   
 
 0.687
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.678
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.674
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
   
 
 0.672
F6Y518_CANLF
IRF-3 domain-containing protein.
   
 
 0.661
IFIT1
Interferon induced protein with tetratricopeptide repeats 1.
   
  
 0.644
HELZ2
Helicase with zinc finger 2.
   
 0.638
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.