STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIGYF2GRB10 interacting GYF protein 2. (1318 aa)    
Predicted Functional Partners:
TOX4
TOX high mobility group box family member 4.
   
  
 0.879
RBMX2
RNA binding motif protein X-linked 2.
   
  
 0.874
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
   
 
 0.841
USP4
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
  
 0.808
TNRC6C
Trinucleotide repeat containing adaptor 6C.
   
 
 0.798
KCTD4
Potassium channel tetramerization domain containing 4.
      
 0.785
ZNF598
Zinc finger protein 598.
    
 
 0.765
GRB10
Growth factor receptor bound protein 10.
    
 
 0.755
LOC100685282
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.737
J9PAM4_CANLF
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
    
 
 0.737
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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