STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFHX2Zinc finger homeobox 2. (2572 aa)    
Predicted Functional Partners:
EXOSC9
Exosome component 9.
      
 0.702
INPP5K
Inositol polyphosphate-5-phosphatase K.
      
 0.701
RPH3AL
Rabphilin 3A like (without C2 domains).
      
 0.671
TECPR2
Tectonin beta-propeller repeat containing 2.
   
  
 0.632
RERE
Arginine-glutamic acid dipeptide repeats.
   
  
 0.628
OLFML2B
Olfactomedin like 2B.
   
 
 0.562
SCN9A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.561
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator.
      
 0.555
WNK1
WNK lysine deficient protein kinase 1.
   
  
 0.543
POU2F2
POU domain protein.
   
 
 0.540
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.