SOX5 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SOX5

SRY-box 5. (763 aa)

Predicted Functional Partners:

FOXB1

0.791

SATB2

0.765

FEZF2

0.740

TBR1

0.731

SHOX

0.724

SOX6

0.708

PRDM16

0.690

SPEF2

0.681

ACAN

0.675

SOX13

0.645

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	SOX5	ENSCAFP00000065577	ENSCAFP00000017109	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	SRY-box 5.	0.675
ACAN	SOX6	ENSCAFP00000065577	ENSCAFP00000056192	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	SRY-box 6.	0.685
FEZF2	SATB2	ENSCAFP00000010567	ENSCAFP00000036183	FEZ family zinc finger 2.	DNA-binding protein SATB.	0.741
FEZF2	SOX5	ENSCAFP00000010567	ENSCAFP00000017109	FEZ family zinc finger 2.	SRY-box 5.	0.740
FEZF2	TBR1	ENSCAFP00000010567	ENSCAFP00000014694	FEZ family zinc finger 2.	T-box brain transcription factor 1.	0.779
FOXB1	PRDM16	ENSCAFP00000034829	ENSCAFP00000039059	Forkhead box B1.	PR/SET domain 16.	0.705
FOXB1	SHOX	ENSCAFP00000034829	ENSCAFP00000016165	Forkhead box B1.	Short stature homeobox.	0.762
FOXB1	SOX5	ENSCAFP00000034829	ENSCAFP00000017109	Forkhead box B1.	SRY-box 5.	0.791
PRDM16	FOXB1	ENSCAFP00000039059	ENSCAFP00000034829	PR/SET domain 16.	Forkhead box B1.	0.705
PRDM16	SHOX	ENSCAFP00000039059	ENSCAFP00000016165	PR/SET domain 16.	Short stature homeobox.	0.638
PRDM16	SOX5	ENSCAFP00000039059	ENSCAFP00000017109	PR/SET domain 16.	SRY-box 5.	0.690
SATB2	FEZF2	ENSCAFP00000036183	ENSCAFP00000010567	DNA-binding protein SATB.	FEZ family zinc finger 2.	0.741
SATB2	SOX5	ENSCAFP00000036183	ENSCAFP00000017109	DNA-binding protein SATB.	SRY-box 5.	0.765
SATB2	TBR1	ENSCAFP00000036183	ENSCAFP00000014694	DNA-binding protein SATB.	T-box brain transcription factor 1.	0.961
SHOX	FOXB1	ENSCAFP00000016165	ENSCAFP00000034829	Short stature homeobox.	Forkhead box B1.	0.762
SHOX	PRDM16	ENSCAFP00000016165	ENSCAFP00000039059	Short stature homeobox.	PR/SET domain 16.	0.638
SHOX	SOX5	ENSCAFP00000016165	ENSCAFP00000017109	Short stature homeobox.	SRY-box 5.	0.724
SOX13	SOX5	ENSCAFP00000048855	ENSCAFP00000017109	SRY-box 13.	SRY-box 5.	0.645
SOX13	SOX6	ENSCAFP00000048855	ENSCAFP00000056192	SRY-box 13.	SRY-box 6.	0.496
SOX5	ACAN	ENSCAFP00000017109	ENSCAFP00000065577	SRY-box 5.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.675