STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MECRMitochondrial trans-2-enoyl-CoA reductase. (367 aa)    
Predicted Functional Partners:
UQCRB
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
  
 0.882
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
   
  
 0.783
CRYZL1
PKS_ER domain-containing protein.
  
  
 0.664
LOC100856647
PKS_ER domain-containing protein.
  
  
 0.660
TIMM8A
Translocase of inner mitochondrial membrane 8A; Belongs to the small Tim family.
   
  
 0.628
CBR4
Carbonyl reductase 4.
   
 0.611
LAP3
Leucine aminopeptidase 3.
   
  
 0.611
LIPT2
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
   
  
 0.586
FASN
Fatty acid synthase.
  
 0.584
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.568
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.