STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DISC1DISC1 scaffold protein. (848 aa)    
Predicted Functional Partners:
NDEL1
NudE neurodevelopment protein 1 like 1.
    
 
 0.893
FBXW7
F-box and WD repeat domain containing 7.
    
 
 0.815
PDE4B
Phosphodiesterase.
    
 
 0.770
TSNAX
Uncharacterized protein.
 
 
  
 0.706
ZNF804A
Zinc finger protein 804A.
      
 0.674
FBXW9
F-box and WD repeat domain containing 9.
   
 
 0.583
NDE1
NudE neurodevelopment protein 1.
    
 
 0.564
ENSCAFP00000052879
Uncharacterized protein.
    
 
 0.564
PCM1
Pericentriolar material 1.
    
 
 0.535
TRAF3IP1
TRAF3 interacting protein 1.
    
 
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.