| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C4BPB | CRP | ENSCAFP00000038337 | ENSCAFP00000017329 | Complement component 4 binding protein beta. | Pentaxin. | 0.690 |
| C4BPB | HRG | ENSCAFP00000038337 | ENSCAFP00000020009 | Complement component 4 binding protein beta. | Histidine rich glycoprotein. | 0.427 |
| C4BPB | LOC479668 | ENSCAFP00000038337 | ENSCAFP00000029992 | Complement component 4 binding protein beta. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.479 |
| CP | CRP | ENSCAFP00000046239 | ENSCAFP00000017329 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Pentaxin. | 0.698 |
| CP | ENSCAFP00000045471 | ENSCAFP00000046239 | ENSCAFP00000045471 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Aspartate aminotransferase. | 0.468 |
| CP | FGB | ENSCAFP00000046239 | ENSCAFP00000012386 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] | 0.534 |
| CP | GOT1 | ENSCAFP00000046239 | ENSCAFP00000013922 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Aspartate aminotransferase. | 0.532 |
| CP | GOT2 | ENSCAFP00000046239 | ENSCAFP00000012308 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Aspartate aminotransferase. | 0.467 |
| CP | LOC479668 | ENSCAFP00000046239 | ENSCAFP00000029992 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.906 |
| CP | LOC611632 | ENSCAFP00000046239 | ENSCAFP00000043372 | Ceruloplasmin; Belongs to the multicopper oxidase family. | Uncharacterized protein; Belongs to the multicopper oxidase family. | 0.806 |
| CRP | C4BPB | ENSCAFP00000017329 | ENSCAFP00000038337 | Pentaxin. | Complement component 4 binding protein beta. | 0.690 |
| CRP | CP | ENSCAFP00000017329 | ENSCAFP00000046239 | Pentaxin. | Ceruloplasmin; Belongs to the multicopper oxidase family. | 0.698 |
| CRP | ENSCAFP00000045471 | ENSCAFP00000017329 | ENSCAFP00000045471 | Pentaxin. | Aspartate aminotransferase. | 0.865 |
| CRP | FGB | ENSCAFP00000017329 | ENSCAFP00000012386 | Pentaxin. | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] | 0.661 |
| CRP | GOT1 | ENSCAFP00000017329 | ENSCAFP00000013922 | Pentaxin. | Aspartate aminotransferase. | 0.864 |
| CRP | GOT2 | ENSCAFP00000017329 | ENSCAFP00000012308 | Pentaxin. | Aspartate aminotransferase. | 0.864 |
| CRP | HRG | ENSCAFP00000017329 | ENSCAFP00000020009 | Pentaxin. | Histidine rich glycoprotein. | 0.758 |
| CRP | IL6 | ENSCAFP00000017329 | ENSCAFP00000053025 | Pentaxin. | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] | 0.665 |
| CRP | LOC479668 | ENSCAFP00000017329 | ENSCAFP00000029992 | Pentaxin. | Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...] | 0.684 |
| CRP | LOC611632 | ENSCAFP00000017329 | ENSCAFP00000043372 | Pentaxin. | Uncharacterized protein; Belongs to the multicopper oxidase family. | 0.698 |
