node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRX | FIZ1 | ENSCAFP00000006035 | ENSCAFP00000039294 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | FLT3 interacting zinc finger 1. | 0.506 |
CRX | NR2E3 | ENSCAFP00000006035 | ENSCAFP00000061829 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | NR LBD domain-containing protein. | 0.875 |
CRX | NRL | ENSCAFP00000006035 | ENSCAFP00000017429 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | Neural retina leucine zipper. | 0.803 |
CRX | RAX | ENSCAFP00000006035 | ENSCAFP00000000135 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | Retina and anterior neural fold homeobox. | 0.426 |
CRX | SP4 | ENSCAFP00000006035 | ENSCAFP00000003893 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | Sp4 transcription factor. | 0.679 |
CRX | THRB | ENSCAFP00000006035 | ENSCAFP00000045245 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | Thyroid hormone receptor beta. | 0.508 |
CRX | ZNF784 | ENSCAFP00000006035 | ENSCAFP00000040346 | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | Zinc finger protein 784. | 0.452 |
FIZ1 | CRX | ENSCAFP00000039294 | ENSCAFP00000006035 | FLT3 interacting zinc finger 1. | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | 0.506 |
FIZ1 | NRL | ENSCAFP00000039294 | ENSCAFP00000017429 | FLT3 interacting zinc finger 1. | Neural retina leucine zipper. | 0.779 |
FIZ1 | RAX | ENSCAFP00000039294 | ENSCAFP00000000135 | FLT3 interacting zinc finger 1. | Retina and anterior neural fold homeobox. | 0.877 |
NR2E3 | CRX | ENSCAFP00000061829 | ENSCAFP00000006035 | NR LBD domain-containing protein. | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | 0.875 |
NR2E3 | NRL | ENSCAFP00000061829 | ENSCAFP00000017429 | NR LBD domain-containing protein. | Neural retina leucine zipper. | 0.764 |
NRL | CRX | ENSCAFP00000017429 | ENSCAFP00000006035 | Neural retina leucine zipper. | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family. | 0.803 |
NRL | FIZ1 | ENSCAFP00000017429 | ENSCAFP00000039294 | Neural retina leucine zipper. | FLT3 interacting zinc finger 1. | 0.779 |
NRL | NR2E3 | ENSCAFP00000017429 | ENSCAFP00000061829 | Neural retina leucine zipper. | NR LBD domain-containing protein. | 0.764 |
NRL | PIGN | ENSCAFP00000017429 | ENSCAFP00000065619 | Neural retina leucine zipper. | Phosphatidylinositol glycan anchor biosynthesis class N. | 0.730 |
NRL | RAX | ENSCAFP00000017429 | ENSCAFP00000000135 | Neural retina leucine zipper. | Retina and anterior neural fold homeobox. | 0.725 |
NRL | SP4 | ENSCAFP00000017429 | ENSCAFP00000003893 | Neural retina leucine zipper. | Sp4 transcription factor. | 0.767 |
NRL | THRB | ENSCAFP00000017429 | ENSCAFP00000045245 | Neural retina leucine zipper. | Thyroid hormone receptor beta. | 0.667 |
NRL | TRPT1 | ENSCAFP00000017429 | ENSCAFP00000021508 | Neural retina leucine zipper. | tRNA phosphotransferase 1. | 0.784 |