NRL protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

NRL

Neural retina leucine zipper. (257 aa)

Predicted Functional Partners:

CRX

0.803

TRPT1

0.784

VXN

0.783

FIZ1

0.779

SP4

0.767

NR2E3

0.764

ZNF784

0.739

PIGN

0.730

RAX

0.725

THRB

0.667

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRX	FIZ1	ENSCAFP00000006035	ENSCAFP00000039294	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	FLT3 interacting zinc finger 1.	0.506
CRX	NR2E3	ENSCAFP00000006035	ENSCAFP00000061829	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	NR LBD domain-containing protein.	0.875
CRX	NRL	ENSCAFP00000006035	ENSCAFP00000017429	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	Neural retina leucine zipper.	0.803
CRX	RAX	ENSCAFP00000006035	ENSCAFP00000000135	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	Retina and anterior neural fold homeobox.	0.426
CRX	SP4	ENSCAFP00000006035	ENSCAFP00000003893	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	Sp4 transcription factor.	0.679
CRX	THRB	ENSCAFP00000006035	ENSCAFP00000045245	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	Thyroid hormone receptor beta.	0.508
CRX	ZNF784	ENSCAFP00000006035	ENSCAFP00000040346	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	Zinc finger protein 784.	0.452
FIZ1	CRX	ENSCAFP00000039294	ENSCAFP00000006035	FLT3 interacting zinc finger 1.	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	0.506
FIZ1	NRL	ENSCAFP00000039294	ENSCAFP00000017429	FLT3 interacting zinc finger 1.	Neural retina leucine zipper.	0.779
FIZ1	RAX	ENSCAFP00000039294	ENSCAFP00000000135	FLT3 interacting zinc finger 1.	Retina and anterior neural fold homeobox.	0.877
NR2E3	CRX	ENSCAFP00000061829	ENSCAFP00000006035	NR LBD domain-containing protein.	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	0.875
NR2E3	NRL	ENSCAFP00000061829	ENSCAFP00000017429	NR LBD domain-containing protein.	Neural retina leucine zipper.	0.764
NRL	CRX	ENSCAFP00000017429	ENSCAFP00000006035	Neural retina leucine zipper.	Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors (By similarity); Belongs to the paired homeobox family.	0.803
NRL	FIZ1	ENSCAFP00000017429	ENSCAFP00000039294	Neural retina leucine zipper.	FLT3 interacting zinc finger 1.	0.779
NRL	NR2E3	ENSCAFP00000017429	ENSCAFP00000061829	Neural retina leucine zipper.	NR LBD domain-containing protein.	0.764
NRL	PIGN	ENSCAFP00000017429	ENSCAFP00000065619	Neural retina leucine zipper.	Phosphatidylinositol glycan anchor biosynthesis class N.	0.730
NRL	RAX	ENSCAFP00000017429	ENSCAFP00000000135	Neural retina leucine zipper.	Retina and anterior neural fold homeobox.	0.725
NRL	SP4	ENSCAFP00000017429	ENSCAFP00000003893	Neural retina leucine zipper.	Sp4 transcription factor.	0.767
NRL	THRB	ENSCAFP00000017429	ENSCAFP00000045245	Neural retina leucine zipper.	Thyroid hormone receptor beta.	0.667
NRL	TRPT1	ENSCAFP00000017429	ENSCAFP00000021508	Neural retina leucine zipper.	tRNA phosphotransferase 1.	0.784