node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATIC | GMPS | ENSCAFP00000021114 | ENSCAFP00000036506 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Uncharacterized protein. | 0.665 |
ATIC | IMPDH1 | ENSCAFP00000021114 | ENSCAFP00000002420 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.964 |
ATIC | IMPDH2 | ENSCAFP00000021114 | ENSCAFP00000017589 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.801 |
ATIC | LOC100856570 | ENSCAFP00000021114 | ENSCAFP00000013625 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
ATIC | LOC487740 | ENSCAFP00000021114 | ENSCAFP00000036914 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
CTPS1 | GMPS | ENSCAFP00000004062 | ENSCAFP00000036506 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Uncharacterized protein. | 0.857 |
CTPS1 | IMPDH1 | ENSCAFP00000004062 | ENSCAFP00000002420 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.672 |
CTPS1 | IMPDH2 | ENSCAFP00000004062 | ENSCAFP00000017589 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.721 |
CTPS1 | LOC100856570 | ENSCAFP00000004062 | ENSCAFP00000013625 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.599 |
CTPS1 | LOC487740 | ENSCAFP00000004062 | ENSCAFP00000036914 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.599 |
CTPS1 | PA2G4 | ENSCAFP00000004062 | ENSCAFP00000000143 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. | Proliferation-associated 2G4. | 0.550 |
ENSCAFP00000066135 | GMPS | ENSCAFP00000066135 | ENSCAFP00000036506 | MGS domain-containing protein. | Uncharacterized protein. | 0.650 |
ENSCAFP00000066135 | IMPDH1 | ENSCAFP00000066135 | ENSCAFP00000002420 | MGS domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.662 |
ENSCAFP00000066135 | IMPDH2 | ENSCAFP00000066135 | ENSCAFP00000017589 | MGS domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.793 |
ENSCAFP00000066135 | LOC100856570 | ENSCAFP00000066135 | ENSCAFP00000013625 | MGS domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
ENSCAFP00000066135 | LOC487740 | ENSCAFP00000066135 | ENSCAFP00000036914 | MGS domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
EPHX2 | GDA | ENSCAFP00000012415 | ENSCAFP00000002645 | Epoxide hydrolase 2. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.430 |
EPHX2 | IMPDH1 | ENSCAFP00000012415 | ENSCAFP00000002420 | Epoxide hydrolase 2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.833 |
EPHX2 | IMPDH2 | ENSCAFP00000012415 | ENSCAFP00000017589 | Epoxide hydrolase 2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.834 |
EPHX2 | LOC100856570 | ENSCAFP00000012415 | ENSCAFP00000013625 | Epoxide hydrolase 2. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.454 |