STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDZD8PDZ domain containing 8. (1169 aa)    
Predicted Functional Partners:
LNPK
Lunapark, ER junction formation factor.
    
 
 0.861
ZFYVE27
Zinc finger FYVE-type containing 27.
      
 0.781
RAB7A
Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...]
   
 
 0.755
STARD3
StAR related lipid transfer domain containing 3.
      
 0.739
LOC102153864
Uncharacterized protein.
      
 0.735
VAPA
VAMP associated protein A.
   
 
 0.709
NSD3
Nuclear receptor binding SET domain protein 3.
      
 0.708
MON1A
MON1 homolog A, secretory trafficking associated.
      
 0.690
VAPB
VAMP associated protein B and C.
   
 
 0.680
ACBD5
Acyl-CoA-binding domain-containing protein 5; Binds medium- and long-chain acyl-CoA esters.
   
  
 0.679
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.