STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CACUL1CDK2 associated cullin domain 1; Belongs to the cullin family. (235 aa)    
Predicted Functional Partners:
NEDD8
NEDD8 ubiquitin like modifier.
    
 
 0.778
SPOPL
Speckle type BTB/POZ protein like.
   
 
 0.727
TRIO
Trio Rho guanine nucleotide exchange factor.
   
 
 0.723
UBXN7
UBX domain-containing protein 7.
   
 
 0.717
NSUN4
NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
  
 0.711
SPOP
Speckle type BTB/POZ protein.
   
 
 0.682
GPS1
G protein pathway suppressor 1.
   
 
 0.679
CAND1
Cullin associated and neddylation dissociated 1.
   
 
 0.678
RNF7
Ring finger protein 7.
   
 
 0.676
SKP2
S-phase kinase associated protein 2.
    
 
 0.675
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.