STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARIH2RBR-type E3 ubiquitin transferase. (491 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
   
 
 0.963
RNF7
Ring finger protein 7.
   
 
 0.824
NEDD8
NEDD8 ubiquitin like modifier.
   
 
 0.785
UBE2L3
Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.757
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.
      
 0.723
FBXO41
F-box protein 41.
      
 0.707
EIF2B5
Eukaryotic translation initiation factor 2B subunit epsilon.
 
 
  
 0.704
ELOB
Elongin B.
    
 
 0.692
KIF3C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.675
CBFA2T3
CBFA2/RUNX1 translocation partner 3.
   
  
 0.645
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.