STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF683Zinc finger protein 683. (492 aa)    
Predicted Functional Partners:
DNAJC14
J domain-containing protein.
   
  
 0.876
TMC5
Transmembrane channel-like protein.
   
 
 0.876
SPATS1
Spermatogenesis associated serine rich 1.
      
 0.875
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
  
 0.873
KNTC1
Kinetochore associated 1.
      
 0.824
HPS5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
   
  
 0.789
ZNF500
Zinc finger protein 500.
  
 
0.712
S1PR5
Sphingosine-1-phosphate receptor 5.
   
  
 0.594
ESCO1
Establishment of sister chromatid cohesion N-acetyltransferase 1.
      
 0.591
AGPS
Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
      
 0.583
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.