STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEG1Heart development protein with EGF like domains 1. (1415 aa)    
Predicted Functional Partners:
KRIT1
KRIT1 ankyrin repeat containing.
   
 
 0.916
MAP6
Microtubule associated protein 6.
    
 
 0.693
CCDC102A
Coiled-coil domain containing 102A.
   
  
 0.643
KLF7
Kruppel like factor 7.
   
 
 0.605
ASB2
Ankyrin repeat and SOCS box containing 2.
   
 
 0.603
KTN1
Kinectin 1.
   
 
 0.599
SH2D3C
SH2 domain containing 3C.
   
 
 0.562
CASKIN2
CASK interacting protein 2.
   
 
 0.560
FUT1
L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family.
      
 0.560
REM1
RRAD and GEM like GTPase 1.
   
 
 0.543
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.