STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN14Protein tyrosine phosphatase non-receptor type 14. (1245 aa)    
Predicted Functional Partners:
NUAK2
NUAK family kinase 2.
   
  
 0.791
AMOTL2
Angiomotin like 2.
   
 
 0.730
ISM1
Isthmin 1.
    
 
 0.717
ARHGEF17
Rho guanine nucleotide exchange factor 17.
   
  
 0.711
LATS1
Large tumor suppressor kinase 1.
    
 
 0.710
RASSF8
Ras association domain family member 8.
   
  
 0.687
DOCK5
Dedicator of cytokinesis 5; Belongs to the DOCK family.
   
  
 0.676
HES3
Hes family bHLH transcription factor 3.
      
 0.674
WWC1
WW and C2 domain containing 1.
   
 
 0.671
WWC2
WW and C2 domain containing 2.
   
 
 0.666
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.