STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIDO1Death inducer-obliterator 1. (2212 aa)    
Predicted Functional Partners:
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
   
 
 0.805
KDM7A
Lysine demethylase 7A.
   
  
 0.802
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 
 0.797
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
   
 
 0.782
SETD1B
SET domain containing 1B, histone lysine methyltransferase.
   
 
 0.700
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 
 0.690
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
   
  
 0.683
CCNB3
G2/mitotic-specific cyclin-B3; Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).
      
 0.674
ZNF804A
Zinc finger protein 804A.
   
  
 0.646
MRPL43
Mitochondrial ribosomal protein L43.
   
  
 0.645
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.