CD3G protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD2	CD247	ENSCAFP00000014445	ENSCAFP00000041707	CD2 molecule.	Uncharacterized protein.	0.943
CD2	CD3D	ENSCAFP00000014445	ENSCAFP00000038117	CD2 molecule.	CD3d molecule.	0.950
CD2	CD3E	ENSCAFP00000014445	ENSCAFP00000052947	CD2 molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.938
CD2	CD3G	ENSCAFP00000014445	ENSCAFP00000018809	CD2 molecule.	CD3g molecule.	0.901
CD2	ITK	ENSCAFP00000014445	ENSCAFP00000025891	CD2 molecule.	Tyrosine-protein kinase.	0.908
CD2	TRAT1	ENSCAFP00000014445	ENSCAFP00000042632	CD2 molecule.	T cell receptor associated transmembrane adaptor 1.	0.507
CD2	ZAP70	ENSCAFP00000014445	ENSCAFP00000047083	CD2 molecule.	Tyrosine-protein kinase.	0.619
CD247	CD2	ENSCAFP00000041707	ENSCAFP00000014445	Uncharacterized protein.	CD2 molecule.	0.943
CD247	CD3D	ENSCAFP00000041707	ENSCAFP00000038117	Uncharacterized protein.	CD3d molecule.	0.999
CD247	CD3E	ENSCAFP00000041707	ENSCAFP00000052947	Uncharacterized protein.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.999
CD247	CD3G	ENSCAFP00000041707	ENSCAFP00000018809	Uncharacterized protein.	CD3g molecule.	0.999
CD247	F1PJW6_CANLF	ENSCAFP00000041707	ENSCAFP00000034553	Uncharacterized protein.	Uncharacterized protein.	0.955
CD247	IGKC	ENSCAFP00000041707	ENSCAFP00000010929	Uncharacterized protein.	Immunoglobulin kappa constant.	0.905
CD247	ITK	ENSCAFP00000041707	ENSCAFP00000025891	Uncharacterized protein.	Tyrosine-protein kinase.	0.951
CD247	SYK	ENSCAFP00000041707	ENSCAFP00000054848	Uncharacterized protein.	Tyrosine-protein kinase.	0.990
CD247	TRAT1	ENSCAFP00000041707	ENSCAFP00000042632	Uncharacterized protein.	T cell receptor associated transmembrane adaptor 1.	0.768
CD247	ZAP70	ENSCAFP00000041707	ENSCAFP00000047083	Uncharacterized protein.	Tyrosine-protein kinase.	0.999
CD3D	CD2	ENSCAFP00000038117	ENSCAFP00000014445	CD3d molecule.	CD2 molecule.	0.950
CD3D	CD247	ENSCAFP00000038117	ENSCAFP00000041707	CD3d molecule.	Uncharacterized protein.	0.999
CD3D	CD3E	ENSCAFP00000038117	ENSCAFP00000052947	CD3d molecule.	T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...]	0.999