STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPEF1Serine/threonine-protein phosphatase with EF-hands. (661 aa)    
Predicted Functional Partners:
ASB12
Ankyrin repeat and SOCS box containing 12.
    
 
 0.889
CPNE1
RNA binding motif protein 12.
      
 0.887
PWWP2B
PWWP domain-containing protein.
      
 0.882
RLIM
Ring finger protein, LIM domain interacting.
   
  
 0.856
ATP8B2
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 
 0.820
ADAM8
ADAM metallopeptidase domain 8.
   
  
 0.794
GPR101
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.734
ZNF518B
Zinc finger protein 518B.
    
 
 0.596
IGBP1
Immunoglobulin binding protein 1.
    
 
 0.573
ASIC3
Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.568
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.