STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOBTB1Rho related BTB domain containing 1. (698 aa)    
Predicted Functional Partners:
KEAP1
Kelch like ECH associated protein 1.
   
  0.907
KLHL13
Kelch like family member 13.
   
  0.906
KLHL9-2
Uncharacterized protein.
    
  0.906
ITSN2
Intersectin 2.
    
 
 0.833
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.827
RIMS4
Regulating synaptic membrane exocytosis 4.
      
 0.804
WDR93
WD repeat domain 93.
      
 0.800
ITSN1
Intersectin 1.
   
 
 0.764
LOC100856635
Uncharacterized protein.
    
 
 0.763
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
   
 
 0.756
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.