STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELZ2Helicase with zinc finger 2. (2974 aa)    
Predicted Functional Partners:
EXOSC10
Exosome component 10.
   
 0.915
EXOSC5
Exosome component 5.
   
 0.855
EXOSC7
Exosome component 7.
   
 
 0.790
MTREX
Mtr4 exosome RNA helicase.
   
 
 0.786
EXOSC1
Exosome component 1.
   
 
 0.786
EPSTI1
Epithelial stromal interaction 1.
   
  
 0.784
EXOSC9
Exosome component 9.
   
 
 0.781
EXOSC4
Exosome component 4.
   
 0.778
EXOSC6
Exosome component 6.
   
 0.778
EXOSC8
Exosome component 8.
   
 
 0.778
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.