STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRHL3Grainyhead like transcription factor 3. (607 aa)    
Predicted Functional Partners:
ZNF333
Zinc finger protein 333.
    
 
 0.650
IRF6
Interferon regulatory factor 6.
   
 
 0.630
ZNF750
Zinc finger protein 750.
   
  
 0.629
TGM1
Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family.
   
  
 0.575
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
   
  
 0.572
PDZRN4
PDZ domain containing ring finger 4.
   
  
 0.569
LONRF2
LON peptidase N-terminal domain and ring finger 2.
      
 0.565
OVOL1
Ovo like transcriptional repressor 1.
   
  
 0.563
ARHGAP29
Rho GTPase activating protein 29.
   
  
 0.559
NIPAL4
NIPA like domain containing 4.
   
  
 0.534
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.