STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGSL1Regulator of G protein signaling like 1. (1160 aa)    
Predicted Functional Partners:
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
    
   0.719
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 
 0.568
RGS6
Regulator of G protein signaling 6.
   
  
 0.563
RAD50
RAD50 double strand break repair protein.
    
   0.529
STMN4
Stathmin 4.
   
 
 0.520
TMEM88B
Transmembrane protein 88B.
      
 0.515
RGS13
Regulator of G protein signaling 13.
      
 0.512
MAD2L1BP
MAD2L1 binding protein.
      
 0.502
HIF3A
Hypoxia inducible factor 3 subunit alpha.
   
  
 0.500
TAF8
TATA-box binding protein associated factor 8.
      
 0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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