Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTNNB1 | MAGI2 | ENSCAFP00000007783 | ENSCAFP00000006489 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | 0.946 |
| CTNNB1 | MAGI3 | ENSCAFP00000007783 | ENSCAFP00000019378 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | 0.958 |
| CTNNB1 | RAPGEF2 | ENSCAFP00000007783 | ENSCAFP00000066461 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adre [...] | 0.470 |
| DDN | MAGI2 | ENSCAFP00000012871 | ENSCAFP00000006489 | Dendrin. | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | 0.847 |
| DDN | MAGI3 | ENSCAFP00000012871 | ENSCAFP00000019378 | Dendrin. | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | 0.749 |
| LPAR2 | MAGI3 | ENSCAFP00000020893 | ENSCAFP00000019378 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | 0.719 |
| MAGI2 | CTNNB1 | ENSCAFP00000006489 | ENSCAFP00000007783 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | 0.946 |
| MAGI2 | DDN | ENSCAFP00000006489 | ENSCAFP00000012871 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | Dendrin. | 0.847 |
| MAGI2 | MAGI3 | ENSCAFP00000006489 | ENSCAFP00000019378 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | 0.913 |
| MAGI2 | RAPGEF2 | ENSCAFP00000006489 | ENSCAFP00000066461 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adre [...] | 0.939 |
| MAGI2 | RAPGEF6 | ENSCAFP00000006489 | ENSCAFP00000001071 | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | Uncharacterized protein. | 0.926 |
| MAGI3 | CTNNB1 | ENSCAFP00000019378 | ENSCAFP00000007783 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | 0.958 |
| MAGI3 | DDN | ENSCAFP00000019378 | ENSCAFP00000012871 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Dendrin. | 0.749 |
| MAGI3 | LPAR2 | ENSCAFP00000019378 | ENSCAFP00000020893 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. | 0.719 |
| MAGI3 | MAGI2 | ENSCAFP00000019378 | ENSCAFP00000006489 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Membrane associated guanylate kinase, WW and PDZ domain containing 2. | 0.913 |
| MAGI3 | MARK1 | ENSCAFP00000019378 | ENSCAFP00000040265 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Non-specific serine/threonine protein kinase. | 0.719 |
| MAGI3 | MIPEP | ENSCAFP00000019378 | ENSCAFP00000010600 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Mitochondrial intermediate peptidase. | 0.789 |
| MAGI3 | PHTF1 | ENSCAFP00000019378 | ENSCAFP00000013558 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Putative homeodomain transcription factor 1. | 0.831 |
| MAGI3 | RAPGEF2 | ENSCAFP00000019378 | ENSCAFP00000066461 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adre [...] | 0.920 |
| MAGI3 | RAPGEF6 | ENSCAFP00000019378 | ENSCAFP00000001071 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. | Uncharacterized protein. | 0.920 |
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