STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDR2Discoidin domain receptor tyrosine kinase 2. (866 aa)    
Predicted Functional Partners:
FAM171A1
Family with sequence similarity 171 member A1.
      
 0.767
ITGA2
Integrin subunit alpha 2; Belongs to the integrin alpha chain family.
   
  
 0.614
STARD7
StAR related lipid transfer domain containing 7.
      
 0.500
EGFR
Receptor protein-tyrosine kinase.
   
 
0.498
RHBDL2
Rhomboid-related protein 2; Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
  
 0.487
MGAT5
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.
      
 0.485
COL1A1
Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).
   
 
 0.479
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
   
  
 0.461
LPIN1
Lipin 1.
      
 0.458
EML4
EMAP like 4.
      
 0.457
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.