MKI67 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

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Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPM	CCNA2	ENSCAFP00000016776	ENSCAFP00000006129	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Cyclin A2; Belongs to the cyclin family.	0.933
ASPM	CDK1	ENSCAFP00000016776	ENSCAFP00000019027	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.903
ASPM	CENPE	ENSCAFP00000016776	ENSCAFP00000015964	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.964
ASPM	CENPF	ENSCAFP00000016776	ENSCAFP00000018561	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Centromere protein F.	0.975
ASPM	CEP55	ENSCAFP00000016776	ENSCAFP00000011659	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Centrosomal protein 55.	0.920
ASPM	KIF2C	ENSCAFP00000016776	ENSCAFP00000007130	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.912
ASPM	MKI67	ENSCAFP00000016776	ENSCAFP00000019524	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Marker of proliferation Ki-67.	0.923
ASPM	SPAG5	ENSCAFP00000016776	ENSCAFP00000027622	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Sperm associated antigen 5.	0.909
ASPM	TOP2A	ENSCAFP00000016776	ENSCAFP00000042966	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.977
CCNA2	ASPM	ENSCAFP00000006129	ENSCAFP00000016776	Cyclin A2; Belongs to the cyclin family.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.933
CCNA2	CDK1	ENSCAFP00000006129	ENSCAFP00000019027	Cyclin A2; Belongs to the cyclin family.	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	0.999
CCNA2	CENPE	ENSCAFP00000006129	ENSCAFP00000015964	Cyclin A2; Belongs to the cyclin family.	Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.908
CCNA2	CENPF	ENSCAFP00000006129	ENSCAFP00000018561	Cyclin A2; Belongs to the cyclin family.	Centromere protein F.	0.920
CCNA2	CEP55	ENSCAFP00000006129	ENSCAFP00000011659	Cyclin A2; Belongs to the cyclin family.	Centrosomal protein 55.	0.896
CCNA2	KIF2C	ENSCAFP00000006129	ENSCAFP00000007130	Cyclin A2; Belongs to the cyclin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.897
CCNA2	MKI67	ENSCAFP00000006129	ENSCAFP00000019524	Cyclin A2; Belongs to the cyclin family.	Marker of proliferation Ki-67.	0.923
CCNA2	SPAG5	ENSCAFP00000006129	ENSCAFP00000027622	Cyclin A2; Belongs to the cyclin family.	Sperm associated antigen 5.	0.905
CCNA2	TOP2A	ENSCAFP00000006129	ENSCAFP00000042966	Cyclin A2; Belongs to the cyclin family.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.953
CDK1	ASPM	ENSCAFP00000019027	ENSCAFP00000016776	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.903
CDK1	CCNA2	ENSCAFP00000019027	ENSCAFP00000006129	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.	Cyclin A2; Belongs to the cyclin family.	0.999