STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1JProtein phosphatase, Mg2+/Mn2+ dependent 1J. (612 aa)    
Predicted Functional Partners:
PLK2
Polo like kinase 2.
   
  
 0.789
DDB2
Damage specific DNA binding protein 2.
   
  
 0.785
RILP
Rab interacting lysosomal protein.
   
  
 0.637
MTMR9
Myotubularin related protein 9.
   
  
 0.524
NT5DC2
5'-nucleotidase domain containing 2.
      
 0.522
PPM1F
Protein phosphatase, Mg2+/Mn2+ dependent 1F.
      
0.515
PPTC7
Protein phosphatase; Belongs to the PP2C family.
   
  
 0.502
PPM1K
Protein phosphatase, Mg2+/Mn2+ dependent 1K.
      
 0.502
ENOPH1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
      
 0.497
DOLPP1
Dolichyldiphosphatase 1.
      
 0.497
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.