STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDD2Rhomboid domain containing 2. (396 aa)    
Predicted Functional Partners:
KANSL1
KAT8 regulatory NSL complex subunit 1.
      
 0.832
BROX
BRO1 domain and CAAX motif containing.
   
  
 0.800
NOP53
NOP53 ribosome biogenesis factor.
   
  
 0.730
USP3
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.707
HABP2
Hyaluronan binding protein 2.
    
 
 0.701
ANO7
Anoctamin.
   
  
 0.677
RPS5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
   
  
 0.670
KANK1
KN motif and ankyrin repeat domains 1.
    
 
 0.668
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1.
    
 
 0.637
ZNF667
Zinc finger protein 667.
      
 0.634
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.