STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC611332Uncharacterized protein. (401 aa)    
Predicted Functional Partners:
DLA88
DLA class I histocompatibility antigen, A9/A9 alpha chain; Involved in the presentation of foreign antigens to the immune system.
    
 0.927
KLRD1
Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
   
0.920
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.912
LOC486692
C-type lectin domain-containing protein.
     
 
0.900
ENSCAFP00000046354
Uncharacterized protein.
     
 
0.900
SYK
Tyrosine-protein kinase.
   
 0.537
LCK
Tyrosine-protein kinase.
   
  0.516
FYN
Tyrosine-protein kinase.
   
  0.512
KLRK1
Killer cell lectin like receptor K1.
   
 
0.510
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
  0.506
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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