STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTBP3Latent transforming growth factor beta binding protein 3. (680 aa)    
Predicted Functional Partners:
B9D2
Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]
   
 0.911
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.882
TGFB3
Transforming growth factor beta 3.
   
 0.847
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
    
 0.733
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
    
 
 0.690
FSD1
Fibronectin type III and SPRY domain containing 1.
    
 
 0.689
FSTL3
Follistatin like 3.
    
 
 0.680
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
 
  
 
 0.672
GDF11
Growth differentiation factor 11.
    
 
 0.657
LTBP1
Latent transforming growth factor beta binding protein 1.
     
0.656
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.