node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD31 | HORMAD1 | ENSCAFP00000042196 | ENSCAFP00000017772 | Ankyrin repeat domain 31. | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | 0.691 |
ANKRD31 | HORMAD2 | ENSCAFP00000042196 | ENSCAFP00000018347 | Ankyrin repeat domain 31. | HORMA domain-containing protein 2; Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid- pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break- independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for norm [...] | 0.528 |
ANKRD31 | LOC100687249 | ENSCAFP00000042196 | ENSCAFP00000032258 | Ankyrin repeat domain 31. | Cor1 domain-containing protein. | 0.611 |
ANKRD31 | LOC102152531 | ENSCAFP00000042196 | ENSCAFP00000031959 | Ankyrin repeat domain 31. | Cor1 domain-containing protein. | 0.611 |
ANKRD31 | MAJIN | ENSCAFP00000042196 | ENSCAFP00000035001 | Ankyrin repeat domain 31. | Membrane anchored junction protein. | 0.675 |
ANKRD31 | SYCE3 | ENSCAFP00000042196 | ENSCAFP00000041157 | Ankyrin repeat domain 31. | Synaptonemal complex central element protein 3. | 0.440 |
ANKRD31 | TERB1 | ENSCAFP00000042196 | ENSCAFP00000030265 | Ankyrin repeat domain 31. | Telomere repeat binding bouquet formation protein 1. | 0.453 |
ANKRD31 | TERB2 | ENSCAFP00000042196 | ENSCAFP00000020123 | Ankyrin repeat domain 31. | Telomere repeat binding bouquet formation protein 2. | 0.676 |
CCDC155 | MAJIN | ENSCAFP00000005475 | ENSCAFP00000035001 | Coiled-coil domain containing 155. | Membrane anchored junction protein. | 0.595 |
CCDC155 | SUN1 | ENSCAFP00000005475 | ENSCAFP00000016590 | Coiled-coil domain containing 155. | Sad1 and UNC84 domain containing 1. | 0.947 |
CCDC155 | TERB1 | ENSCAFP00000005475 | ENSCAFP00000030265 | Coiled-coil domain containing 155. | Telomere repeat binding bouquet formation protein 1. | 0.572 |
CCDC155 | TERB2 | ENSCAFP00000005475 | ENSCAFP00000020123 | Coiled-coil domain containing 155. | Telomere repeat binding bouquet formation protein 2. | 0.681 |
HORMAD1 | ANKRD31 | ENSCAFP00000017772 | ENSCAFP00000042196 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Ankyrin repeat domain 31. | 0.691 |
HORMAD1 | LOC100687249 | ENSCAFP00000017772 | ENSCAFP00000032258 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Cor1 domain-containing protein. | 0.756 |
HORMAD1 | LOC102152531 | ENSCAFP00000017772 | ENSCAFP00000031959 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Cor1 domain-containing protein. | 0.756 |
HORMAD1 | MAJIN | ENSCAFP00000017772 | ENSCAFP00000035001 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Membrane anchored junction protein. | 0.647 |
HORMAD1 | SUN1 | ENSCAFP00000017772 | ENSCAFP00000016590 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Sad1 and UNC84 domain containing 1. | 0.483 |
HORMAD1 | SYCE3 | ENSCAFP00000017772 | ENSCAFP00000041157 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Synaptonemal complex central element protein 3. | 0.828 |
HORMAD1 | TERB1 | ENSCAFP00000017772 | ENSCAFP00000030265 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Telomere repeat binding bouquet formation protein 1. | 0.564 |
HORMAD1 | TERB2 | ENSCAFP00000017772 | ENSCAFP00000020123 | HORMA domain-containing protein 1; Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single- stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process b [...] | Telomere repeat binding bouquet formation protein 2. | 0.665 |