STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUOXA2Dual oxidase maturation factor 2. (320 aa)    
Predicted Functional Partners:
DUOX1
Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
 
 0.987
DUOX2
Dual oxidase 2.
 
 
 0.929
NOX5
NADPH oxidase 5.
   
 
 0.785
NAALADL1
N-acetylated alpha-linked acidic dipeptidase like 1.
   
  
 0.683
IYD
Iodotyrosine deiodinase.
   
  
 0.680
MKRN2
Makorin ring finger protein 2.
   
  
 0.671
NOX3
Predicted NADPH oxidase-3.
   
 
 0.658
KLHL18
Kelch like family member 18.
      
 0.636
NOXO1
NADPH oxidase organizer 1.
   
  
 0.636
NOX1
NADPH oxidase 1.
   
 
 0.626
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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