STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A2ML1Alpha-2-macroglobulin like 1. (1446 aa)    
Predicted Functional Partners:
TMEM63C
Transmembrane protein 63C.
      
 0.803
SAMD4B
Sterile alpha motif domain containing 4B.
      
 0.789
GOLGA3
Golgin A3.
      
 0.716
EVPL
Envoplakin.
   
  
 0.698
PPL
Periplakin.
   
  
 0.650
LY6D
Lymphocyte antigen 6 family member D.
      
 0.648
EFHD2
EF-hand domain family member D2.
      
 0.647
BPIFB2
BPI fold containing family B member 2.
      
 0.643
MGAM2
Maltase-glucoamylase 2 (putative).
   
  
 0.596
APOH
Beta-2-glycoprotein 1; Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
   
 
 0.587
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.