STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)    
Predicted Functional Partners:
ZYG11B
Zyg-11 family member B, cell cycle regulator.
   
  
 0.790
GNAT1
Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream eff [...]
     
 0.754
BID
BH3 interacting domain death agonist.
     
  0.750
ANKMY2
Ankyrin repeat and MYND domain containing 2.
   
 
 0.743
ACBD6
Acyl-CoA binding domain containing 6.
   
 
 0.718
DHRS11
Dehydrogenase/reductase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.693
LMAN2L
Lectin, mannose binding 2 like.
   
  
 0.670
ZER1
Zyg-11 related cell cycle regulator.
      
 0.654
PHF20L1
PHD finger protein 20 like 1.
   
  
 0.625
TSPAN13
Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family.
      
 0.610
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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