STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC12Tetratricopeptide repeat domain 12. (709 aa)    
Predicted Functional Partners:
C10H22orf23
Chromosome 10 C22orf23 homolog.
   
    0.805
ANKK1
Ankyrin repeat and kinase domain containing 1.
 
  
 
 0.707
PIH1D2
PIH1 domain containing 2.
   
 
 0.686
CFAP300
Cilia and flagella associated protein 300.
    
 
 0.681
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.618
WDHD1
WD repeat and HMG-box DNA binding protein 1.
    
 
 0.610
AHSA1
Activator of HSP90 ATPase activity 1.
   
 
 0.582
CFAP298
Uncharacterized protein.
      
 0.570
DNAAF1
Dynein assembly factor 1, axonemal.
   
 
 0.562
ZMYND10
Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family.
   
  
 0.546
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.