STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM20BFAM20B glycosaminoglycan xylosylkinase. (409 aa)    
Predicted Functional Partners:
ENSCAFP00000049139
VWFA domain-containing protein.
   
    0.682
SLCO1A2
Solute carrier organic anion transporter family member.
   
    0.665
NAT9
N-acetyltransferase 9 (putative).
 
      0.655
FAM20C
FAM20C golgi associated secretory pathway kinase.
  
 
 
0.632
CHPF2
Hexosyltransferase.
      
 0.619
ENAM
Enamelin.
   
 
 0.616
XYLT1
Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones.
   
  
 0.592
WASF1
WASP family member 1.
   
  
 0.568
POR
Cytochrome p450 oxidoreductase.
 
      0.566
UXS1
UDP-glucuronate decarboxylase 1.
   
  
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.