STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL28Kelch like family member 28. (578 aa)    
Predicted Functional Partners:
RNF166
Ring finger protein 166.
    
 
 0.923
FBXO28
F-box protein 28.
   
  
 0.736
CORO7
Coronin; Belongs to the WD repeat coronin family.
   
 
 0.722
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
      
 0.677
NAA25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit.
      
 0.588
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.583
RC3H2
Ring finger and CCCH-type domains 2.
   
 
 0.532
LRSAM1
Leucine rich repeat and sterile alpha motif containing 1.
   
 
 0.526
GPHB5
Glycoprotein hormone subunit beta 5.
   
  
 0.520
TRIM13
Tripartite motif containing 13.
   
 
 0.516
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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