STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIP6Thyroid hormone receptor interactor 6. (478 aa)    
Predicted Functional Partners:
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
    
 0.902
TRIP10
Thyroid hormone receptor interactor 10.
   
  
 0.764
FBXL13
F-box and leucine rich repeat protein 13.
      
 0.681
SVIL
Supervillin.
   
 
 0.639
SLC12A9
Solute carrier family 12 member 9.
 
 
  
 0.600
ZNF358
Zinc finger protein 358.
   
 
 0.600
HAUS3
HAUS augmin like complex subunit 3.
   
 
 0.585
HAUS1
HAUS augmin like complex subunit 1.
   
 
 0.570
SAV1
Salvador family WW domain containing protein 1.
   
 
 0.552
LATS2
Non-specific serine/threonine protein kinase.
   
 
 0.541
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.