STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPREB3V-set pre-B cell surrogate light chain 3. (121 aa)    
Predicted Functional Partners:
LOC100687054
Ig-like domain-containing protein.
   
 
 0.842
CD79B
CD79b molecule.
   
 
 0.833
CD79A
B-cell antigen receptor complex-associated protein alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]
   
 
 0.751
FCRLA
Fc receptor like A.
   
 
 0.714
CD19
CD19 molecule.
   
  
 0.683
FCMR
Fc fragment of IgM receptor.
   
 
 0.660
BLK
Tyrosine-protein kinase.
   
 
 0.636
F1PG87_CANLF
Uncharacterized protein.
   
 
 0.623
MZB1
Marginal zone B and B1 cell specific protein.
   
  
 0.577
ENSCAFP00000044033
Ig-like domain-containing protein.
   
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.